Herpes Test – IgM and IgG

Dear Dr. Rob:

I have a question in relation to the Immunoglobulin value
in a person infected with herpes simplex virus. Please
explain IgM and IgG.


Dr Rob’s Response:

Dear Poster Who Asks about IgG and IgM:

Initially the antibody that appears is IgM. It is non-specific
but it occurs very rapidly. The more specific antibody
and the one that will control infections is the IgG antibody
and that appears later. As a result during the initial outbreak,
one would expect IgM and over time the IgM would be
replaced by IgG. Were you to contract a second dose of
herpes, it would be IgG not IgM that would increase.


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