Cold sores, also called fever blisters or oral herpes, are very common and usually clear up on their own. This guide covers what causes them, how to avoid passing them on, and when to get help, with links to all our doctors' answers about cold sores and oral herpes.
This is general information, not medical advice. It does not replace a visit with a doctor or clinic.
Cold sores are caused by herpes simplex, usually HSV-1. Most people pick up the virus as children through close contact such as kissing. Once you have it, it stays in the body for life and can cause a cold sore from time to time.
A cold sore usually starts with tingling, itching or burning. Within about 48 hours, small fluid-filled blisters appear, then burst and crust over. They usually start to heal within 10 days. Not every mouth sore is a cold sore: a blister inside the mouth is often a mouth ulcer.
From the first tingle until the sore has completely healed. Don’t kiss anyone or have oral sex during that time, because the virus can cause genital herpes in a partner. Wash your hands after touching the sore, and avoid sharing items that touch saliva. Never kiss a newborn baby if you have a cold sore.
Illness or fever, sun, periods, injury, stress and surgery can all trigger cold sores. If sun is a trigger, a sunblock lip balm (SPF 15 or above) can help. Skin procedures like laser resurfacing and peels can also trigger them, so tell your provider beforehand.
A pharmacist can suggest creams to ease pain and antiviral creams, which work best at the first tingle. Pain relievers and plenty of fluids help. A doctor may prescribe antiviral tablets if cold sores are large, painful or keep coming back.
See a doctor if a cold sore hasn’t started to heal within 10 days, is very large or painful, is near your eye, if a child has swollen, painful gums and mouth sores, or if you have a weakened immune system.
Questions readers have sent in over the years, answered by herpes.com’s contributing doctors. Answers reflect each doctor’s view at the time they were written; for current guidance, see the sources below and talk to your own provider.
Medical disclaimer: The information on herpes.com is for general education only and is not a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your doctor with any questions about a medical condition. Read our full disclaimer. Guide published October 2026.
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